THE STUDY - Here you will find my summary of the pantothenic acid in the treatment of acne study conducted by Dr Lit-Hung Leung with ammendments in 1998. A link to the entire study is provided if you want to read the entire thing.
PANTOTHENIC ACID - Information on pantothenic acid in general. University research concluding its use for several known ailments.
"The food and nutrition board of the Institute of Medicine felt that the existing scientific evidence was insufficient to calculate an RDA for Pantothenic Acid....Pantothenic acid is not known to be toxic in humans. The only adverse effect was diahorrea resulting from very high intakes of up to 10 to 20gms/day....due to the lack of adverse effects the Food and Nutrition board did not set a tolerable upper limit of intake for pantothenic acid."
B5 FACT SHEET - University research fact sheet on the sources, uses and toxicity (or lack thereof) of this vitamin.
"Toxicity to Pantothenic Acid has not been reported. The upper limit of safety has not been determined due to lack of data subtantiating adverse effects at high intakes. The Food and Nutrition board of the institute of Medicine recommends that pantothenic acid should only be consumed from food sources."
B5 ARTICLE - Article by Elson M. Haas M.D published in Staying Healthy with Nutrition: The complete guide to Diet and Nutritional Medicine.
"It is possible that if b5 is taken without other b vitamins, it may create a metabolic imbalance." [Hence why it is recommended to take a b-complex or good multi-vitamin during b5 therapy...Ed "Teenagers are more likely to experience a deficiency because their diets often include high amounts of 'fast foods', sugars and refined flours (all low in b vitamins.) And the problem may be compounded because the acne often associated....is commonly treated with tetracycline antibiotics which reduce the intestinal bacteria and thereby the production of pantothenic acid in the colon."]
RISK MODEL FOR UPPER INTAKES OF NUTRIENTS - A very interesting page detailing how you should look out for adverse side effects when megadosing supplements. Always something to keep in mind.
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