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HIV/AIDS Page 2



Getting Tested

Types of Testing


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Where to Test


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When to Test: Going Through The Window Period

If you test during the window period, your test may come back negative, even though you are infected with HIV!

The Window Period is the period after a person is infected during which he or she does not test positive for HIV. Usually testing positive for HIV means testing positive for HIV antibodies. After a person is infected, the body's immune system develops antibodies, which attack the HIV. However, it takes time to develop enough antibodies for the antibodies to show up in an antibody test. Most people develop enough antibodies to get a positive antibody test result within 3 months, and almost all people develop enough antibodies to get a positive antibody test result within 6 months. In rare cases, it may take as long as a year or two to develop enough antibodies to get a positive antibody test.

There is also a test which looks for the virus itself. Enough copies of HIV are produced to give a positive result on this test within about two weeks after being exposed to HIV. However, this test--the PCR or Polymerase Chain Reaction is very expensive.

It is a good idea to wait the duration of Window Period after your last possible exposure to HIV, and then retest. If you are exposed regularly, you should test every six months!

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Interpreting Results


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Where Did HIV Come From?

Take a look at some of HIV's history!

Treatment and Vaccinations?



Healing: Putting It All Together

Brief suggestions about exercise, nutrition, restoring immune function, combatting opportunistic infections, and combatting HIV itself.

A Brief Outline of Healing Therapies

Therapies That Use Prescription Drugs: (More Info. on Combatting the HIV Virus)

Vaccinations?

See IAVI, Vaccine Science--but beware--some vaccinations use live viruses, and may be dangerous; and vaccinations are never 100% effective, and are never tested for a lifetime until people start getting the vaccinations! Options looked at include live vaccinations, made by attaching HIV proteins to live, and generally harmless bacteria and viruses (the live bacteria and virus bring the HIV proteins to the body's immune system which then learns to recognize and respond to the proteins); live vaccines, made from modified HIV (considered very risky at this point); killed vaccines, made with inactive parts of the HIV virus itself; and injections of single proteins from HIV. Though most vaccinations are injected into the blood, scientists are also exploring ways to provide mucosal immunity against HIV. Mucosal responses may be different than blood responses to viruses and vaccination, and the mucosal area may provide a place for HIV and other diseases to live even when they are destroyed in the blood. It seems that the antibody response in the mucosal areas may be crucial in combatting HIV and other sexually-transmitted diseases. Today mucosal immunity is being researched. Unfortunately,immune responses themselves are still not that well understood according to Myron S.Cohen and Joseph Eron's HIV/AIDS Case Management 18, and all HIV vaccinations are still in the trial stages. Again according to Cohen and Eron, most vaccination research is done in the U.S. and on the varieties of human immunodeficiency virus that are found in the U.S.

In their review of a book by Jon Cohen, Shots in the Dark: the Wayward Search for an AIDS Vaccine (2001), Medscape's Medpulse editors write:

"To date, we have failed to develop any vaccine capable of blocking infection of a sexually transmitted pathogen at a mucosal surface, although not for lack of effort. Clinical trials for vaccines designed to prevent gonorrhea and herpes have failed."

Clearly, much needs to be learned about the immune response in the mucosal areas! And HIV in countries outside of the U.S. needs to be studied. But this does not mean that finding a vaccine is hopeless! (However, as noted above, vaccinations may not be 100% effective; therefore, many people think a vaccination program might leave people vulnerable because people, feeling secure with a vaccine, might stop taking care to prevent HIV and even other 'curable' STD's; perhaps vaccination cannot be that effective without good STD prevention and treatment programs, too.)

Also, according to Researchers in Kenya (HLA Typing May Be Advisable Before HIV Vaccine Trials; reprinted in Medscape last month), responses induced by vaccines may not work with certain types of HIV which resist these responses. The researchers suggests mapping of "local alleles" to determine ways they resist the immune sytem's responses.

(In this research, Dr. Rupert Kaul from the University of Toronto and colleagues identified two novel HLA class I alleles among commercial sex workers in Kenya, as well as among lower-risk women, that restrict cytotoxic T lymphocyte responses to locally prevalent HIV-1 clade A. [Reuters Health Information, October, 2002].)



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HIV/AIDS Quiz: Test Your Knowledge


 

AIDS Scavenger Hunt!



Useful Numbers

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Great Links:



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Great Reading

These books are generally available at libraries. If not at your library, you can get them through interlibrary loan. They're also available at Amazon.com.



Resources



This page was created by C. E. Whitehead, July, 2001; last updated May, 2002


[Email the author: [email protected]][About the Author]

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